The world is going to miss Nora Ephron's wry wit and observations of life and people.
Sleepless in Seattle: I smile every time I think of Tom Hanks and The Other Dude getting all weepy [sic] over The Dirty Dozen. That scene in When Harry Met Sally. Silkwood - a play turned into a movie that was compelling and disturbing, despite the rough edges. I'm not so sure they didn't make the movie more powerful. The charm of "You've Got Mail" and its underlying look at the mall-ification of America. Despite the sometimes difficult subjects she tackled, she was always cheerful and optimistic.
She has clearly inspired a lot of people with her tongue-in-cheek style; that cheerful wryness can be seen in the work of people as diverse as artist Maira Kalman and journalist, author and columnist Gail Collins.
The NY Times has a good obituary.
And Prospero, writing in The Economist, has a great review of her last book, "I Remember Nothing and Other Reflections"
A remarkable talent, a remarkable person, a remarkable woman.